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Research Article

Unresponsiveness to Glucantime Treatment in Iranian Cutaneous Leishmaniasis due to Drug-Resistant Leishmania tropica Parasites

  • Ramtin Hadighi,

    Affiliation: School of Public Health and Institute of Public Health Research, Tehran University of Medical Sciences, Tehran, Iran

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  • Mehdi Mohebali mail,

    To whom correspondence should be addressed. E-mail: Marc.Ouellette@crchul.ulaval.ca (MO), E-mail: mmohebali@hotmail.com (MM)

    Affiliation: School of Public Health and Institute of Public Health Research, Tehran University of Medical Sciences, Tehran, Iran

    X
  • Patrick Boucher,

    Affiliation: Centre de Recherche en Infectiologie and Département de Biologie Médicale, Université Laval, Québec, Canada

    X
  • Homa Hajjaran,

    Affiliation: School of Public Health and Institute of Public Health Research, Tehran University of Medical Sciences, Tehran, Iran

    X
  • Ali Khamesipour,

    Affiliation: Center for Research and Training in Skin Diseases and Leprosy, Tehran University of Medical Sciences, Tehran, Iran

    X
  • Marc Ouellette mail

    To whom correspondence should be addressed. E-mail: Marc.Ouellette@crchul.ulaval.ca (MO), E-mail: mmohebali@hotmail.com (MM)

    Affiliation: Centre de Recherche en Infectiologie and Département de Biologie Médicale, Université Laval, Québec, Canada

    X
  • Published: April 18, 2006
  • DOI: 10.1371/journal.pmed.0030162

About the Authors

Ramtin Hadighi, Mehdi Mohebali, Homa Hajjaran
School of Public Health and Institute of Public Health Research, Tehran University of Medical Sciences, Tehran, Iran
Patrick Boucher, Marc Ouellette
Centre de Recherche en Infectiologie and Département de Biologie Médicale, Université Laval, Québec, Canada
Ali Khamesipour
Center for Research and Training in Skin Diseases and Leprosy, Tehran University of Medical Sciences, Tehran, Iran

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

RH, PB, and HH performed the experiments and analyzed the data. RH, MM, AK, and MO designed the experiment, analyzed the data, and contributed to writing the paper.