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Research Article

Determining Effective Methadone Doses for Individual Opioid-Dependent Patients

  • Jodie A Trafton mail,

    To whom correspondence should be addressed. E-mail: Jodie.Trafton@va.gov

    Affiliation: Center for Health Care Evaluation, VA Palo Alto Health Care System and Stanford University School of Medicine, Menlo Park, California, United States of America

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  • Jared Minkel,

    Affiliations: Center for Health Care Evaluation, VA Palo Alto Health Care System and Stanford University School of Medicine, Menlo Park, California, United States of America, Department of Psychology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

    X
  • Keith Humphreys

    Affiliation: Center for Health Care Evaluation, VA Palo Alto Health Care System and Stanford University School of Medicine, Menlo Park, California, United States of America

    X
  • Published: February 07, 2006
  • DOI: 10.1371/journal.pmed.0030080

About the Authors

Jodie A Trafton, Jared Minkel, Keith Humphreys
Center for Health Care Evaluation, VA Palo Alto Health Care System and Stanford University School of Medicine, Menlo Park, California, United States of America
Jared Minkel
Department of Psychology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Corresponding Author

Email: Jodie.Trafton@va.gov

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

JAT conceived and designed the analysis described, managed data acquisition, analysis, and interpretation, and drafted the manuscript. JM conducted data acquisition and assisted with data analysis, presentation, and interpretation. KH conceived and designed the MOST study. JM and KH critically revised the manuscript for important intellectual content. JAT, JM, and KH approved the final version of the manuscript.