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Research Article

Analysis of Prion Strains by PrPSc Profiling in Sporadic Creutzfeldt–Jakob Disease

  • Gaby Schoch,

    Affiliation: Institute of Neuropathology, University Hospital of Zürich, Zürich, Switzerland

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  • Harald Seeger,

    Affiliation: Institute of Neuropathology, University Hospital of Zürich, Zürich, Switzerland

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  • Julien Bogousslavsky,

    Affiliation: Department of Neurology and Division of Neuropathology, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland

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  • Markus Tolnay,

    Affiliation: Institute of Pathology, Department of Neuropathology, University Hospital Basel, Basel, Switzerland

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  • Robert Charles Janzer,

    Affiliation: Department of Neurology and Division of Neuropathology, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland

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  • Adriano Aguzzi,

    Affiliation: Institute of Neuropathology, University Hospital of Zürich, Zürich, Switzerland

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  • Markus Glatzel mail

    To whom correspondence should be addressed. E-mail: m.glatzel@uke.uni-hamburg.de

    Affiliation: Institute of Neuropathology, University Hospital of Zürich, Zürich, Switzerland

    ¤ Current address: Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

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  • Published: December 20, 2005
  • DOI: 10.1371/journal.pmed.0030014

About the Authors

Gaby Schoch, Harald Seeger, Adriano Aguzzi, Markus Glatzel
Institute of Neuropathology, University Hospital of Zürich, Zürich, Switzerland
Julien Bogousslavsky, Robert Charles Janzer
Department of Neurology and Division of Neuropathology, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
Markus Tolnay
Institute of Pathology, Department of Neuropathology, University Hospital Basel, Basel, Switzerland

Corresponding Author

Email: m.glatzel@uke.uni-hamburg.de

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

GS, HS, AA, and MG analyzed the data. HS, JB, MT, and RCJ enrolled patients. AA and MG designed the study. GS, HS, MT, RCJ, AA, and MG contributed to writing the paper.