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Research Article

Maternal Malaria and Gravidity Interact to Modify Infant Susceptibility to Malaria

  • Theonest K Mutabingwa,

    Affiliations: MOMS Project, Malaria Antigen Discovery Program, Seattle Biomedical Research Institute, Seattle, Washington, United States of America, Gates Malaria Partnership, London School of Hygiene and Tropical Medicine, London, United Kingdom, National Institute for Medical Research, Muheza Designated District Hospital, Muheza-Tanga, Tanzania

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  • Melissa C Bolla,

    Affiliation: MOMS Project, Malaria Antigen Discovery Program, Seattle Biomedical Research Institute, Seattle, Washington, United States of America

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  • Jin-Long Li,

    Affiliation: MOMS Project, Malaria Antigen Discovery Program, Seattle Biomedical Research Institute, Seattle, Washington, United States of America

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  • Gonzalo J Domingo,

    Affiliation: MOMS Project, Malaria Antigen Discovery Program, Seattle Biomedical Research Institute, Seattle, Washington, United States of America

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  • Xiaohong Li,

    Affiliation: Statistical Center for HIV/AIDS Research & Prevention, Department of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

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  • Michal Fried,

    Affiliation: MOMS Project, Malaria Antigen Discovery Program, Seattle Biomedical Research Institute, Seattle, Washington, United States of America

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  • Patrick E Duffy mail

    To whom correspondence should be addressed. E-mail: pduffy@sbri.org

    Affiliations: MOMS Project, Malaria Antigen Discovery Program, Seattle Biomedical Research Institute, Seattle, Washington, United States of America, Department of Immunology, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America

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  • Published: November 08, 2005
  • DOI: 10.1371/journal.pmed.0020407

About the Authors

Theonest K Mutabingwa, Melissa C Bolla, Jin-Long Li, Gonzalo J Domingo, Michal Fried, Patrick E Duffy
MOMS Project, Malaria Antigen Discovery Program, Seattle Biomedical Research Institute, Seattle, Washington, United States of America
Theonest K Mutabingwa
Gates Malaria Partnership, London School of Hygiene and Tropical Medicine, London, United Kingdom
Theonest K Mutabingwa
National Institute for Medical Research, Muheza Designated District Hospital, Muheza-Tanga, Tanzania
Xiaohong Li
Statistical Center for HIV/AIDS Research & Prevention, Department of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
Patrick E Duffy
Department of Immunology, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America

Corresponding Author

Email: pduffy@sbri.org

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

The study was designed by TKM, MF, and PED. Clinical studies were coordinated by TKM, laboratory studies were coordinated by GJD, MF, and PED, and data management was coordinated by JLL. Statistical analysis was performed by MCB, JLL, and XL. MCB and PED wrote the report with assistance from the other authors.