Advertisement
Research Article

Marked Differences in Human Melanoma Antigen-Specific T Cell Responsiveness after Vaccination Using a Functional Microarray

  • Daniel S Chen equal contributor,

    equal contributor Contributed equally to this work with: Daniel S Chen, Yoav Soen

    Affiliations: Department of Internal Medicine/Division of Oncology, Stanford University, Stanford, California, United States of America, Howard Hughes Medical Institute, Stanford University, Stanford, California, United States of America

    X
  • Yoav Soen equal contributor,

    equal contributor Contributed equally to this work with: Daniel S Chen, Yoav Soen

    Affiliation: Department of Biochemistry, Stanford University, Stanford, California, United States of America

    X
  • Tor B Stuge,

    Affiliation: Department of Medicine, Stanford University, Stanford, California, United States of America

    X
  • Peter P Lee,

    Affiliation: Department of Medicine, Stanford University, Stanford, California, United States of America

    X
  • Jeffrey S Weber,

    Affiliation: Norris Cancer Center, University of Southern California, Los Angeles, California, United States of America

    X
  • Patrick O Brown,

    Affiliations: Howard Hughes Medical Institute, Stanford University, Stanford, California, United States of America, Department of Biochemistry, Stanford University, Stanford, California, United States of America

    X
  • Mark M Davis mail

    To whom correspondence should be addressed. E-mail: mdavis@cmgm.stanford.edu

    Affiliations: Howard Hughes Medical Institute, Stanford University, Stanford, California, United States of America, Department of Microbiology and Immunology, Stanford University, Stanford, California, United States of America

    X
  • Published: September 20, 2005
  • DOI: 10.1371/journal.pmed.0020265

About the Authors

Daniel S Chen
Department of Internal Medicine/Division of Oncology, Stanford University, Stanford, California, United States of America
Daniel S Chen, Patrick O Brown, Mark M Davis
Howard Hughes Medical Institute, Stanford University, Stanford, California, United States of America
Yoav Soen, Patrick O Brown
Department of Biochemistry, Stanford University, Stanford, California, United States of America
Tor B Stuge, Peter P Lee
Department of Medicine, Stanford University, Stanford, California, United States of America
Jeffrey S Weber
Norris Cancer Center, University of Southern California, Los Angeles, California, United States of America
Mark M Davis
Department of Microbiology and Immunology, Stanford University, Stanford, California, United States of America

Corresponding Author

Email: mdavis@cmgm.stanford.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

DSC and YS conceived of the experiments and designed the study. DSC, YS, and TBS performed the experiments. DSC, YS, and TBS analyzed the data. JSW enrolled patients. DSC, YS, TBS, JSW, POB, and MMD contributed to writing the paper. POB and MMD suggested ideas and experiments.