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Research Article

Preclinical Assessment of HIV Vaccines and Microbicides by Repeated Low-Dose Virus Challenges

  • Roland R Regoes mail,

    To whom correspondence should be addressed. E-mail: rregoes@emory.edu

    Affiliation: Department of Biology, Emory University, Atlanta, Georgia, United States of America

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  • Ira M Longini Jr,

    Affiliation: Department of Biostatistics, Rollins School of Public Health, Emory University, Atlanta, Georgia, United States of America

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  • Mark B Feinberg,

    Affiliations: Departments of Medicine and Microbiology and Immunology, Emory University School of Medicine and the Emory Vaccine Center, Atlanta, Georgia, United States of America, Merck Vaccine Division, Merck, West Point, Pennsylvania, United States of America

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  • Silvija I Staprans

    Affiliation: Departments of Medicine and Microbiology and Immunology, Emory University School of Medicine and the Emory Vaccine Center, Atlanta, Georgia, United States of America

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  • Published: July 19, 2005
  • DOI: 10.1371/journal.pmed.0020249

About the Authors

Roland R Regoes
Department of Biology, Emory University, Atlanta, Georgia, United States of America
Ira M Longini Jr
Department of Biostatistics, Rollins School of Public Health, Emory University, Atlanta, Georgia, United States of America
Mark B Feinberg, Silvija I Staprans
Departments of Medicine and Microbiology and Immunology, Emory University School of Medicine and the Emory Vaccine Center, Atlanta, Georgia, United States of America
Mark B Feinberg
Merck Vaccine Division, Merck, West Point, Pennsylvania, United States of America

Corresponding Author

Email: rregoes@emory.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

RRR performed the analysis. RRR, IML, MBF, and SIS designed the study and wrote the paper.