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Research Article

Estimation of the Total Parasite Biomass in Acute Falciparum Malaria from Plasma PfHRP2

  • Arjen M Dondorp,

    Affiliations: Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand, Centre for Clinical Vaccinology and Tropical Medicine, Churchill Hospital, Oxford, United Kingdom

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  • Varunee Desakorn,

    Affiliation: Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand

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  • Wirichada Pongtavornpinyo,

    Affiliation: Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand

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  • Duangjai Sahassananda,

    Affiliation: Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand

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  • Kamolrat Silamut,

    Affiliation: Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand

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  • Kesinee Chotivanich,

    Affiliation: Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand

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  • Paul N Newton,

    Affiliations: Centre for Clinical Vaccinology and Tropical Medicine, Churchill Hospital, Oxford, United Kingdom, Wellcome Trust–Mahosot Hospital, Vientiane, Lao People's Democratic Republic

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  • Punnee Pitisuttithum,

    Affiliation: Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand

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  • A. M Smithyman,

    Affiliation: Cellabs, Brookvale, New South Wales, Australia

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  • Nicholas J White mail,

    To whom correspondence should be addressed. E-mail: nickw@tropmedres.ac

    Affiliations: Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand, Centre for Clinical Vaccinology and Tropical Medicine, Churchill Hospital, Oxford, United Kingdom

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  • Nicholas P. J Day

    Affiliations: Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand, Centre for Clinical Vaccinology and Tropical Medicine, Churchill Hospital, Oxford, United Kingdom

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  • Published: August 23, 2005
  • DOI: 10.1371/journal.pmed.0020204

About the Authors

Arjen M Dondorp, Varunee Desakorn, Wirichada Pongtavornpinyo, Duangjai Sahassananda, Kamolrat Silamut, Kesinee Chotivanich, Punnee Pitisuttithum, Nicholas J White, Nicholas P. J Day
Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
Arjen M Dondorp, Paul N Newton, Nicholas J White, Nicholas P. J Day
Centre for Clinical Vaccinology and Tropical Medicine, Churchill Hospital, Oxford, United Kingdom
Paul N Newton
Wellcome Trust–Mahosot Hospital, Vientiane, Lao People's Democratic Republic
A. M Smithyman
Cellabs, Brookvale, New South Wales, Australia

Corresponding Author

Email: nickw@tropmedres.ac

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

AMD and NJW designed the study. AMD and PNN enrolled the patients. VD, DS, KS, KC, PP, and AMS contributed to the laboratory studies. AMD, WP, and NPJD analyzed the data. All authors contributed to writing the paper.