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Research Article

Limited Durability of Viral Control following Treated Acute HIV Infection

  • Daniel E Kaufmann equal contributor,

    equal contributor Contributed equally to this work with: Daniel E Kaufmann, Mathias Lichterfeld

    Affiliation: Partners AIDS Research Center, Infectious Disease Unit, Massachusetts General Hospital and Division of AIDS, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Mathias Lichterfeld equal contributor,

    equal contributor Contributed equally to this work with: Daniel E Kaufmann, Mathias Lichterfeld

    Affiliation: Partners AIDS Research Center, Infectious Disease Unit, Massachusetts General Hospital and Division of AIDS, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Marcus Altfeld,

    Affiliation: Partners AIDS Research Center, Infectious Disease Unit, Massachusetts General Hospital and Division of AIDS, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Marylyn M Addo,

    Affiliation: Partners AIDS Research Center, Infectious Disease Unit, Massachusetts General Hospital and Division of AIDS, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Mary N Johnston,

    Affiliation: Partners AIDS Research Center, Infectious Disease Unit, Massachusetts General Hospital and Division of AIDS, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Paul K Lee,

    Affiliation: Partners AIDS Research Center, Infectious Disease Unit, Massachusetts General Hospital and Division of AIDS, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Bradford S Wagner,

    Affiliation: Partners AIDS Research Center, Infectious Disease Unit, Massachusetts General Hospital and Division of AIDS, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Elizabeth T Kalife,

    Affiliation: Partners AIDS Research Center, Infectious Disease Unit, Massachusetts General Hospital and Division of AIDS, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Daryld Strick,

    Affiliation: Partners AIDS Research Center, Infectious Disease Unit, Massachusetts General Hospital and Division of AIDS, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Eric S Rosenberg,

    Affiliation: Partners AIDS Research Center, Infectious Disease Unit, Massachusetts General Hospital and Division of AIDS, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Bruce D Walker

    Affiliations: Partners AIDS Research Center, Infectious Disease Unit, Massachusetts General Hospital and Division of AIDS, Harvard Medical School, Boston, Massachusetts, United States of America, Howard Hughes Medical Institute, Massachusetts General Hospital and Division of AIDS, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Published: October 26, 2004
  • DOI: 10.1371/journal.pmed.0010036

About the Authors

Daniel E Kaufmann, Mathias Lichterfeld, Marcus Altfeld, Marylyn M Addo, Mary N Johnston, Paul K Lee, Bradford S Wagner, Elizabeth T Kalife, Daryld Strick, Eric S Rosenberg, Bruce D Walker
Partners AIDS Research Center, Infectious Disease Unit, Massachusetts General Hospital and Division of AIDS, Harvard Medical School, Boston, Massachusetts, United States of America
Bruce D Walker
Howard Hughes Medical Institute, Massachusetts General Hospital and Division of AIDS, Harvard Medical School, Boston, Massachusetts, United States of America

Corresponding Author

Email: bwalker@partners.org

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

ESR and BDW designed the study. DEK, ML, MMA, PKL, BSW, ETK, and DS performed the experiments. DEK, ML, MA, ESR, and BDW analyzed the data. MNJ enrolled patients. DEK and ML contributed to writing the paper.