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Research Article

The Molecular Basis for Oat Intolerance in Patients with Celiac Disease

  • Helene Arentz-Hansen,

    Affiliation: Institute of Immunology, Rikshospitalet University Hospital, University of Oslo, Oslo, Norway

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  • Burkhard Fleckenstein,

    Affiliations: Institute of Immunology, Rikshospitalet University Hospital, University of Oslo, Oslo, Norway, Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark

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  • Øyvind Molberg,

    Affiliation: Institute of Immunology, Rikshospitalet University Hospital, University of Oslo, Oslo, Norway

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  • Helge Scott,

    Affiliation: Institute of Pathology, Rikshospitalet University Hospital, University of Oslo, Oslo, Norway

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  • Frits Koning,

    Affiliation: Department of Immunohematology and Blood Transfusion, Leiden University Medical Centre, Leiden, Netherlands

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  • Günther Jung,

    Affiliation: Institute of Organic Chemistry, University of Tbingen, T, Germanyübingen

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  • Peter Roepstorff,

    Affiliation: Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark

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  • Knut E. A Lundin,

    Affiliations: Institute of Immunology, Rikshospitalet University Hospital, University of Oslo, Oslo, Norway, Department of Medicine, Rikshospitalet University Hospital, Oslo, Norway

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  • Ludvig M Sollid

    Affiliation: Institute of Immunology, Rikshospitalet University Hospital, University of Oslo, Oslo, Norway

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  • Published: October 19, 2004
  • DOI: 10.1371/journal.pmed.0010001

About the Authors

Helene Arentz-Hansen, Burkhard Fleckenstein, Øyvind Molberg, Knut E. A Lundin, Ludvig M Sollid
Institute of Immunology, Rikshospitalet University Hospital, University of Oslo, Oslo, Norway
Burkhard Fleckenstein, Peter Roepstorff
Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark
Helge Scott
Institute of Pathology, Rikshospitalet University Hospital, University of Oslo, Oslo, Norway
Frits Koning
Department of Immunohematology and Blood Transfusion, Leiden University Medical Centre, Leiden, Netherlands
Günther Jung
Institute of Organic Chemistry, University of Tbingen, T, Germanyübingen
Knut E. A Lundin
Department of Medicine, Rikshospitalet University Hospital, Oslo, Norway

Corresponding Author

Email: l.m.sollid@labmed.uio.no

Competing Interests

The authors have declared that no competing interests exist. LMS is a member of the editorial board of PLoS Medicine.

Author Contributions

ØM, KEAL, and LMS designed the study. HAH, BF, ØM, HS, FK, GJ, PR, KEAL, and LMS analyzed the data. FK and GJ contributed synthetic peptides for the study. HAH, BF, ØM, HS, FK, GJ, KEAL, and LMS contributed to writing the paper.