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Research Article

Modeling of the Temporal Patterns of Fluoxetine Prescriptions and Suicide Rates in the United States

  • Michael S Milane,

    Affiliations: Center for Pharmacogenomics and Clinical Pharmacology, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, California, United States of America, Department of Psychiatry and Biobehavioral Sciences, University of California Los Angeles, Los Angeles, California, United States of America

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  • Marc A Suchard,

    Affiliation: Department of Biomathematics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America

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  • Ma-Li Wong,

    Affiliations: Center for Pharmacogenomics and Clinical Pharmacology, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, California, United States of America, Department of Psychiatry and Biobehavioral Sciences, University of California Los Angeles, Los Angeles, California, United States of America

    ¤ Current address: Julio Licinio and Ma-Li Wong, Department of Psychiatry and Behavioral Sciences, University of Miami, Miami, Florida, United States of America

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  • Julio Licinio mail

    To whom correspondence should be addressed. E-mail: licinio@miami.edu

    Affiliations: Center for Pharmacogenomics and Clinical Pharmacology, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, California, United States of America, Department of Psychiatry and Biobehavioral Sciences, University of California Los Angeles, Los Angeles, California, United States of America, Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America

    ¤ Current address: Julio Licinio and Ma-Li Wong, Department of Psychiatry and Behavioral Sciences, University of Miami, Miami, Florida, United States of America

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  • Published: June 13, 2006
  • DOI: 10.1371/journal.pmed.0030190

Reader Comments (11)

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Is it just a marker for increased care?

Posted by plosmedicine on 30 Mar 2009 at 23:55 GMT

Author: Richard Hockey
Position: Data Analyst
E-mail: rhockey@optusnet.com.au
Submitted Date: June 14, 2006
Published Date: June 15, 2006
This comment was originally posted as a “Reader Response” on the publication date indicated above. All Reader Responses are now available as comments.

I tend to think that this association is a marker for greater recognition and treatment for depression. However its a brave epidemiologist who would draw any conclusions at all from an ecological association such as this where the outcome is relatively rare.

No competing interests declared.