Advertisement
Research Article

Lung Cancer Occurrence in Never-Smokers: An Analysis of 13 Cohorts and 22 Cancer Registry Studies

  • Michael J Thun mail,

    To whom correspondence should be addressed. E-mail: mthun@cancer.org

    Affiliation: American Cancer Society, Atlanta, Georgia, United States of America

    X
  • Lindsay M Hannan,

    Affiliation: American Cancer Society, Atlanta, Georgia, United States of America

    X
  • Lucile L Adams-Campbell,

    Affiliation: Howard University Cancer Center, Washington, D. C., United States of America

    X
  • Paolo Boffetta,

    Affiliation: International Agency for Research on Cancer (IARC), Lyon, France

    X
  • Julie E Buring,

    Affiliation: Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America

    X
  • Diane Feskanich,

    Affiliation: Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America

    X
  • W. Dana Flanders,

    Affiliations: American Cancer Society, Atlanta, Georgia, United States of America, Rollins School of Public Health, Emory University, Atlanta, Georgia, United States of America

    X
  • Sun Ha Jee,

    Affiliation: Institute for Health Promotion, Graduate School of Public Health, Yonsei University, Seoul, Korea

    X
  • Kota Katanoda,

    Affiliation: Cancer Information Services and Surveillance Division, Center for Cancer Control and Information Services, National Cancer Center, Tokyo, Japan

    X
  • Laurence N Kolonel,

    Affiliation: Cancer Research Center of Hawaii, University of Hawaii, Honolulu, Hawaii, United States of America

    X
  • I-Min Lee,

    Affiliation: Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America

    X
  • Tomomi Marugame,

    Affiliation: Cancer Information Services and Surveillance Division, Center for Cancer Control and Information Services, National Cancer Center, Tokyo, Japan

    X
  • Julie R Palmer,

    Affiliation: Slone Epidemiology Center, Boston University, Boston, Massachusetts, United States of America

    X
  • Elio Riboli,

    Affiliation: International Agency for Research on Cancer (IARC), Lyon, France

    X
  • Tomotaka Sobue,

    Affiliation: Cancer Information Services and Surveillance Division, Center for Cancer Control and Information Services, National Cancer Center, Tokyo, Japan

    X
  • Erika Avila-Tang,

    Affiliation: Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America

    X
  • Lynne R Wilkens,

    Affiliation: Cancer Research Center of Hawaii, University of Hawaii, Honolulu, Hawaii, United States of America

    X
  • Jon M Samet

    Affiliation: Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America

    X
  • Published: September 09, 2008
  • DOI: 10.1371/journal.pmed.0050185

Reader Comments (6)

Post a new comment on this article

Possible contributing factors

Posted by plosmedicine on 31 Mar 2009 at 00:30 GMT

Author: Michael Thun
Position: Vice President of Epidemiology & Surveillance Research
Institution: American Cancer Society
E-mail: mthun@cancer.org
Submitted Date: September 19, 2008
Published Date: September 22, 2008
This comment was originally posted as a “Reader Response” on the publication date indicated above. All Reader Responses are now available as comments.

We appreciate the feedback from readers in regards to the factors that they believe may affect lung cancer risk in neversmokers. Our study simply examined the rate of lung cancer incidence and mortality in different populations. We did not have information to explore possible contributing factors.

No competing interests declared.