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The Ethics of Switch/Simplify in Antiretroviral Trials: Non-Inferior or Just Inferior?

  • Andrew Carr mail,

    Affiliations: Clinical Research Program, Centre for Applied Medical Research, St Vincent's Hospital, Sydney, Australia, HIV/Immunology/Infectious Diseases Unit, St Vincent's Hospital, Sydney, Australia

  • Jennifer Hoy,

    Affiliations: Infectious Diseases Unit, Alfred Hospital, Melbourne, Australia, Department of Infectious Diseases, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Australia

  • Anton Pozniak

    Affiliation: Chelsea and Westminster Hospital, London, United Kingdom

  • Published: July 17, 2012
  • DOI: 10.1371/journal.pmed.1001240

Reader Comments (3)

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Same argument was raised in 2010 & 2011

Posted by hhw233 on 01 Aug 2012 at 10:49 GMT

Dear Authors,

Thank you very much for the nicely written informative article which complies with our argument raised in our published articles in 2010 & 2011:

Alameri, M., Epstein, M. & Johnston, A. 2010. Generic and therapeutic substitutions: are they always ethical in their own terms? Pharm World Sci, 32, 691-5.

Al Ameri, M., Epstein, M. & Johnston, A. 2011. Generic and therapeutic substitution: a response to our critic. Int J Clin Pharm, 33, 881-881.

Best Regards,

Mubarak N. Al Ameri BPharm(Hons) MSc
Clinical Pharmacology
Barts and The London
Charterhouse Square
London, EC1M 6BQ, UK

No competing interests declared.