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Research Article

Initial Severity and Antidepressant Benefits: A Meta-Analysis of Data Submitted to the Food and Drug Administration

  • Irving Kirsch mail,

    To whom correspondence should be addressed. E-mail: i.kirsch@hull.ac.uk

    Affiliation: Department of Psychology, University of Hull, Hull, United Kingdom

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  • Brett J Deacon,

    Affiliation: University of Wyoming, Laramie, Wyoming, United States of America

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  • Tania B Huedo-Medina,

    Affiliation: Center for Health, Intervention, and Prevention, University of Connecticut, Storrs, Connecticut, United States of America

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  • Alan Scoboria,

    Affiliation: Department of Psychology, University of Windsor, Windsor, Ontario, Canada

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  • Thomas J Moore,

    Affiliation: Institute for Safe Medication Practices, Huntingdon Valley, Pennsylvania, United States of America

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  • Blair T Johnson

    Affiliation: Center for Health, Intervention, and Prevention, University of Connecticut, Storrs, Connecticut, United States of America

    X
  • Published: February 26, 2008
  • DOI: 10.1371/journal.pmed.0050045

Reader Comments (48)

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initial severity and antidepressant benefits

Posted by plosmedicine on 31 Mar 2009 at 00:22 GMT

Author: ilse maria zalaman
Position: diplomate psychologist
Institution: ENT-University Hospital Tuebingen
E-mail: isa.zalaman@med.uni-tuebingen.de
Submitted Date: March 03, 2008
Published Date: March 3, 2008
This comment was originally posted as a “Reader Response” on the publication date indicated above. All Reader Responses are now available as comments.

I would like to congratulate the authors on their excellent evidenced based medical paper which probably only had a chance to see the light of day through PLOS. It is wonderful that the time has come where scientists seriously question the interests of organizations and provide data which might interest both patients and professionals. Hopefully NARRATIVE MEDICINE will get a chance again!

Competing interests declared: i declare that i have no competing interests