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Essay

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Why Most Published Research Findings Are False

  • John P. A. Ioannidis
  • Published: August 30, 2005
  • DOI: 10.1371/journal.pmed.0020124

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Error in "Why most published research findings are false"

Posted by plosmedicine on 30 Mar 2009 at 23:46 GMT

Author: Art Owen
Position: Professor of Statistics
Institution: Stanford University
E-mail: owen@stat.stanford.edu
Submitted Date: September 27, 2005
Published Date: October 6, 2005
This comment was originally posted as a “Reader Response” on the publication date indicated above. All Reader Responses are now available as comments.

There is an error in the Table 2 entry for the row with research finding = yes and the column with true relationship = no. Plugging in u=0 should make Table 2 equal to Table 1 but it does not. There should be parentheses starting at c alpha and ending just before the division by R+1.

The PPV formula given for Table 2 is unaffected by this error.

Despite the irony of there being an error in an article with such a title, I found the article useful. It provides a good reminder of the need to think about issues of bias and power and the ratio R.

Competing interests declared: I declare that I have no competing interests.