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Research Article

Physical Activity Attenuates the Genetic Predisposition to Obesity in 20,000 Men and Women from EPIC-Norfolk Prospective Population Study

  • Shengxu Li,

    Affiliation: MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge, United Kingdom

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  • Jing Hua Zhao,

    Affiliation: MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge, United Kingdom

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  • Jian'an Luan,

    Affiliation: MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge, United Kingdom

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  • Ulf Ekelund,

    Affiliation: MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge, United Kingdom

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  • Robert N. Luben,

    Affiliation: Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge, Cambridge, United Kingdom

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  • Kay-Tee Khaw,

    Affiliation: Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge, Cambridge, United Kingdom

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  • Nicholas J. Wareham,

    Affiliation: MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge, United Kingdom

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  • Ruth J. F. Loos mail

    ruth.loos@mrc-epid.cam.ac.uk

    Affiliation: MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge, United Kingdom

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  • Published: August 31, 2010
  • DOI: 10.1371/journal.pmed.1000332

Reader Comments (2)

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Why wasn't this study more diverse?

Posted by HighFatContent on 01 Sep 2010 at 23:12 GMT

I have read the study and can't figure out the point of it.

Yes. Most of us should get more exercise, big people too --- but why were all the participants in this study white/European decent?

We live in a multi-culture society. Why weren't people from other ethnic backgrounds included here?

And why, when the media is declaring our children and teens are fatter than ever, wasn't a broader age group represented? Say 12 - 16, 17 - 24, 25 - 34, etc . . .

It's hard to trust a study that isn't more inclusive to the world we live in, isn't it?

I am surprised nobody has brought up any of these issues.

No competing interests declared.